HPV is known to be transmitted to the head and neck area through oral sex. 25% of mouth cancers and 35% of throat cancers are thought to be possibly associated with HPV. Therefore, for patients found to have oral warts, the HPV treatment and follow-up protocol should be followed as in the treatment of genital warts. First of all, the HPV type is identified. If it is found to be high-risk HPV type, it means that the patient needs strict follow-up. If necessary, the vaccination protocol should be followed completely. For the early diagnosis and treatment of head and neck cancers, patients should be followed up by an Ear, Nose, and Throat Specialist (Otolaryngologist), who is experienced in head and neck surgery.

People who carry HPV in the mouth may spread it from mouth to mouth, from mouth to genital area and from mouth to anus.